The Effect of Ginger Decoction Compress on Pain Reduction in Gout Arthritis Patients
DOI:
10.56566/thrive.v3i1.647Downloads
Abstract
Gout arthritis is a prevalent inflammatory joint disease characterized by hyperuricemia and deposition of monosodium urate crystals in the joints, leading to acute pain and impaired mobility. Conventional management primarily relies on pharmacological therapy such as non-steroidal anti-inflammatory drugs (NSAIDs). While effective, long-term use of these drugs carries risks of gastrointestinal bleeding, renal impairment, and cardiovascular complications. This underscores the need for non-pharmacological alternatives that are safe, cost-effective, and culturally adaptable. Ginger (Zingiber officinale) contains bioactive compounds—gingerol, shogaol, and zingerone—that exhibit anti-inflammatory and analgesic properties. This study aimed to evaluate the effectiveness of ginger decoction compress in reducing pain among patients with gout arthritis in Sunggaling Hamlet. A quasi-experimental two-group pretest-posttest design was applied, involving 44 purposively selected participants. The intervention group (n = 22) received ginger decoction compresses for three consecutive days, while the control group (n = 22) received standard care. Pain intensity was measured using the Visual Analog Scale (VAS). Data were analyzed using paired and independent t-tests with a significance level of p < 0.05. Results showed a significant reduction in pain intensity in the intervention group (from a mean VAS score of 7.2 to 3.1, p < 0.05), whereas the control group showed no meaningful change. These findings support the use of ginger decoction compress as a complementary nursing intervention for pain management in gout arthritis patients.
Keywords:
Gout arthritis Ginger compress Pain Complementary therapy Nursing care.References
Han, X., He, X., Shen, P., Zhang, J., Tang, M., Gao, Y., ... & Wei, Y. (2026). Crystallization and inhibition of monosodium urate monohydrate: advances in mechanistic understanding and perspectives for gout management. Journal of Materials Chemistry B, 14(2), 517-527. https://doi.org/10.1039/D5TB01898F
Herdiana, Y., Wardhana, Y. W., Kurniawansyah, I. S., Gozali, D., Wathoni, N., & Sofian, F. F. (2025). Current status of gout arthritis: Current approaches to gout arthritis treatment: Nanoparticles delivery systems approach. Pharmaceutics, 17(1), 102. https://doi.org/10.3390/pharmaceutics17010102
Zhang, J., Sun, N., Zhang, W., Yue, W., Qu, X., Li, Z., & Xu, G. (2025). The impact of uric acid on musculoskeletal diseases: clinical associations and underlying mechanisms. Frontiers in Endocrinology, 16, 1515176. https://doi.org/10.3390/pharmaceutics17010102
Ahmad, S., Ferdous, J., Zahan, T., Ahamed, M. J., Al-Mamun, A. B. M., & Mahmud, T. (2025). A Complex Case of Knee Osteoarthritis Associated with Synovial Chondromatosis, Gout, and Hypothyroidism: A Multimodal Management Approach. European Journal of Medical and Health Research, 3(5), 41-45. https://doi.org/10.59324/ejmhr.2025.3(5).07
Sisi, C. H. E. N., Zeguang, L. I., Xiaowei, D. E. N. G., & Lijuan, G. A. O. (2025). Advances in Understanding the Mechanisms of Treatment for Gouty Arthritis: A Comprehensive Review. Physiological Research, 74(5), 693. https://doi.org/10.33549/physiolres.935631
Peng, Z., Meng, F., Deng, Q., Huang, Y., Mao, D., Long, Y., ... & Liu, N. (2025). Advances in drug delivery systems for the management of gout and hyperuricemia. Frontiers in Pharmacology, 16, 1660890. https://doi.org/10.3389/fphar.2025.1660890
Zhao, X., Sun, Y., Yang, L., Sun, H., Zhang, X., Sun, H., ... & Wang, X. (2025). Fatty acid metabolism in gouty arthritis: mechanisms to therapeutic targeting. Frontiers in Immunology, 16, 1671548. https://doi.org/10.3389/fimmu.2025.1671548
Jilani, L. Z., Istiyak, M., Bhowmik, A. K., & Sudarsan, A. (2025). From suspected joint tuberculosis to gouty arthritis: a diagnostic journey. International Journal of Burns and Trauma, 15(4), 171. https://doi.org/10.62347/PBRZ2450
Zhang, Y., Zhang, H., Miao, T., Wang, X., Zuo, Y., Zhang, R., ... & Li, N. (2025). Advances in the study of gut microecology and mechanisms of hyperuricemia and gouty arthritis. Frontiers in Immunology, 16, 1738716. https://doi.org/10.3389/fimmu.2025.1738716
Vambe, S. D., Mchavi, C. V., Hough, E., & Bronkhorst, E. (2025). Crystals of pain: navigating gout and its management. The South African General Practitioner, 6(1), 14. https://doi.org/10.36303/SAPJ.0810
Inkum, F., Geng, X., Terkeltaub, R., & Cobo, I. (2025). Connecting the Dots: Gouty Arthritis, Clonal Haematopoiesis and Myeloid Activation, in a Unified Inflammation Model for Atherosclerosis Progression. Joint Bone Spine, 105993. https://doi.org/10.1016/j.jbspin.2025.105993
Mageed, S. S. A., Mohamed, F. A., Sobhy, M., Elosaily, A. H., El-Dessouki, A. M., Ghaiad, H. R., ... & Abdelmaksoud, N. M. (2025). Integrating natural products with modern medicine in the treatment of gouty arthritis: a review. Inflammopharmacology, 1-24. https://doi.org/10.1007/s10787-025-01784-0
Abdel Mageed, S. S., Elimam, H., Elesawy, A. E., Abulsoud, A. I., Raouf, A. A., Tabaa, M. M. E., ... & Doghish, A. S. (2025). Unraveling the impact of miRNAs on gouty arthritis: diagnostic significance and therapeutic opportunities. Naunyn-Schmiedeberg's Archives of Pharmacology, 398(4), 3433-3450. https://doi.org/10.1007/s00210-024-03603-9
McCarty, K. L., Gaffo, A. L., & Diaz-Torne, C. (2025). Gout therapy updated. Therapeutic Advances in Musculoskeletal Disease, 17, 1759720X251384584. https://doi.org/10.1177/1759720X251384584
Chen, X., Zhang, C., Zheng, H., Shi, Q., Chen, B., & Han, J. (2026). Gout Inflammation Time Programming: Molecular Clock from Crystal Triggering to Tissue Remodeling. International Journal of Molecular Sciences, 27(3), 1523. https://doi.org/10.3390/ijms27031523
Pan, X., Cui, G., Wang, L., Xiao, Y., Mei, Y., & Huang, C. (2026). The role of musculoskeletal ultrasound in differentiating gouty arthritis from rheumatoid arthritis. Clinical Rheumatology, 1-8. https://doi.org/10.1007/s10067-025-07921-y
Yang, J., Xu, R., Li, K., Han, J., & Tong, Y. (2025). Comprehensive treatment of gout with traditional chinese medicine: A modern pathophysiological perspective. International Journal of General Medicine, 6783-6801. https://doi.org/10.2147/IJGM.S542924
Azad, F. H., Bhat, T., Naik, M., Mir, M. F., Lahdol, P., & Hussain, M. (2025). Clinical Versus Ultrasound Assessment of Joint Activity in Patients with Asymptomatic Hyperuricemia. Indian Journal of Rheumatology, 20(1), 22-26. https://doi.org/10.1177/09733698241271476
Santos, K. K. R., Chohan, F., Simo, R. E., Chambi-Torres, J. B., & Michel, G. (2025). Severe Tophaceous Polyarticular Gout: A Case Report and Review of Literature. Cureus, 17(2). DOI: 10.7759/cureus.79045
Wang, Y., Zhang, Y., Yu, Z., Bai, Y., Zhu, M., Lei, Y., ... & Xiang, J. (2025). Developing Monosodium Urate Monohydrate Crystals–Induced Gout Model in Rodents and Rabbits. Current Protocols, 5(3), e70114. https://doi.org/10.1002/cpz1.70114
SEMBIRING, M. N. M. (2025). EFFECTIVENESS OF CINNAMON (CINNAMOMUN BURMAN) IN REDUCING PAIN SCALE OF GOUTY ARTHRITIS: LITERATURE REVIEW. Quantum Journal of Medical and Health Sciences, 4(1), 1-14. https://doi.org/10.55197/qjmhs.v4i1.106
Setiyaningsih, Y., Ellina, A. D., & Ambarika, R. (2025). THE EFFECT OF DEEP BREATHING RELAXATION TECHNIQUES AND COLD COMPRESS TECHNIQUES ON PAIN LEVELS IN PATIENTS AFTER CRURAL FRACTURE SURGERY. Nurse and Holistic Care, 5(3), 244-253. https://doi.org/10.33086/nhc.v5i3.8252
Nuryanto, Sugiyanto, & Darusalam. (2025). The good governance of community development based on hamlet system: a case study in Condongcatur village, Indonesia. International Journal of Public Law and Policy, 11(1), 52-65. https://doi.org/10.1504/IJPLAP.2025.143346
Hjermstad, M. J., Fayers, P. M., Haugen, D. F., Caraceni, A., Hanks, G. W., Loge, J. H., ... & European Palliative Care Research Collaborative (EPCRC. (2011). Studies comparing numerical rating scales, verbal rating scales, and visual analogue scales for assessment of pain intensity in adults: a systematic literature review. Journal of pain and symptom management, 41(6), 1073-1093.https://doi.org/10.1016/j.jpainsymman.2010.08.016
Seybert, C., Schimmers, N., Silva, L., Breeksema, J. J., Veraart, J., Bessa, B. S., ... & Oliveira-Maia, A. J. (2025). Quality of reporting on psychological interventions in psychedelic treatments: a systematic review. The Lancet Psychiatry, 12(1), 54-66. https://doi.org/10.1016/S2215-0366(24)00333-X
Bar, L., Brandis, S., Wenke, R., & Marks, D. (2025). Adherence to Compression Stockings for Venous Leg Ulcer Prevention: A Pilot Randomised Controlled Trial and Health Economic Analysis, Evaluating a New Multidimensional Tool (PAMCAI). International Wound Journal, 22(4), e70244. https://doi.org/10.1111/iwj.70244
Hasan, M. J., Islam, S., Sujon, H., Chowdhury, F. I., Islam, M., Ahmed, M., ... & Yasmeen, S. (2025). Research involvement among undergraduate medical students in Bangladesh: a multicenter cross-sectional study. BMC Medical Education, 25(1), 126. https://doi.org/10.1186/s12909-024-06566-w
Shafiei, S. B., Shadpour, S., Pangburn, B., Bentley-McLachlan, M., & de Leon-Casasola, O. (2025). Pain classification using functional near infrared spectroscopy and assessment of virtual reality effects in cancer pain management. Scientific Reports, 15(1), 8954. https://doi.org/10.1038/s41598-025-93678-y
Susanti, Y., Candra, E. L., Anggraeni, R., Jati, R. P., PH, L., & Gouda, A. D. K. (2025). The effect of self-healing butterfly hug on anxiety levels. Journal Of Nursing Practice, 8(2), 407-418. https://doi.org/10.30994/jnp.v8i2.668
Zhao, S., Chen, L., Duan, Y., Wang, H., Liu, C., & Wang, X. (2025). The association of pain phenotype and providing caregiving with depressive symptom trajectory for older adults: a longitudinal analysis using the health and retirement study. BMC geriatrics, 25(1), 270. https://doi.org/10.1186/s12877-025-05926-5
Sakopoulos, S., & Todman, M. (2025). The effects of psychotherapy on single and repeated ketamine infusion (s) therapy for treatment-resistant depression: The convergence of molecular and psychological treatment. International Journal of Molecular Sciences, 26(14), 6673. https://doi.org/10.3390/ijms26146673
Sofia, A. S., & Triyanita, M. (2025). Physiotherapy Management of Right Frozen Shoulder: A Case Report. Majalah Ilmiah Fisioterapi Indonesia, 13(3), 567-574. https://doi.org/10.24843/mifi.000000376
Guest, J., Saraiva, P. P., Ceisler, J., & Datta, N. (2025). Clinical Consequences of Disrupted Feedback Control and Abnormal Circuit Reorganization After Spinal Cord Injury. Traumatic Spinal Cord Injury, 281-317. https://doi.org/10.1007/978-3-031-99890-4_19
Islam, M. U., Nayab, M., & Ansari, A. N. (2021). Effect of dry cupping versus soft and prolonged massage in the management of knee osteoarthritis–a randomized controlled clinical trial. Journal of Complementary and Integrative Medicine, 18(4), 797-804. https://doi.org/10.1515/jcim-2020-0350
Hossain, M. S., Wazed, M. A., Asha, S., Amin, M. R., & Shimul, I. M. (2025). Dietary phytochemicals in health and disease: Mechanisms, clinical evidence, and applications—a comprehensive review. Food Science & Nutrition, 13(3), e70101. https://doi.org/10.1002/fsn3.70101
Khumaidi, A., Murwanti, R., Damayanti, E., & Hertiani, T. (2025). Empirical use, phytochemical, and pharmacological effects in wound healing activities of compounds in Diospyros leaves: A review of traditional medicine for potential new plant-derived drugs. Journal of Ethnopharmacology, 337, 118966. https://doi.org/10.1016/j.jep.2024.118966
Do, A. R., Emami, S. A., & Akaberi, M. (2025). Phytochemical diversity and pharmacological effects of sesquiterpenes from Artemisia spp. Phytochemistry Reviews, 24(2), 1365-1502. https://doi.org/10.1007/s11101-024-09962-8
Lu, Q., Wang, J., Tang, Y., Li, W., & Li, C. (2025). Phytochemical analysis of dried ginger extract and its inhibitory effect and mechanism on Helicobacter pylori and associated ureases. Food & Function, 16(3), 1100-1115. https://doi.org/10.1039/D4FO04991H
Liu, W., Han, X., Cao, X., & Gao, Z. (2025). Consumers' heterogeneous preference for organic ginger: a choice experiment. Asia Pacific Journal of Marketing and Logistics, 37(1), 253-269. https://doi.org/10.1108/APJML-03-2024-0388
Matin, M., Kapoor, B., Gulati, M., Mickael, M. E., Matin, F. B., Kamińska, A., ... & Atanasov, A. G. (2025). Exploring the innovation landscape of ginger: Insights from patent documentation analysis. Current Research in Biotechnology, 100299. https://doi.org/10.1016/j.crbiot.2025.100299
Edo, G. I., Igbuku, U. A., Makia, R. S., Isoje, E. F., Gaaz, T. S., Yousif, E., ... & Umar, H. (2025). Phytochemical profile, therapeutic potentials, nutritional composition, and food applications of ginger: a comprehensive review. Discover Food, 5(1), 1-32. https://doi.org/10.1007/s44187-025-00280-2
License
Copyright (c) 2026 Muhamad Sahid Abdullah, Yayan Hardiansah, Fitrihan Rukmana, Vera Yulandasari

This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with THRIVE Health Science Journal, agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution 4.0 International License (CC-BY License). This license allows authors to use all articles, data sets, graphics, and appendices in data mining applications, search engines, web sites, blogs, and other platforms by providing an appropriate reference. The journal allows the author(s) to hold the copyright without restrictions and will retain publishing rights without restrictions.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in THRIVE Health Science Journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).






